Qsymia long term side effects - Sep 30, 2022 · Along with its needed effects, liraglutide (the active ingredient contained in Saxenda) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking liraglutide: More common. Bladder pain

 
trouble sleeping (insomnia) new or worse irritability acting aggressive, being angry, or violent acting on dangerous impulses an extreme increase in activity and talking (mania) other unusual changes in behavior or mood Serious eye problems which include:. Albertsons dollar5 friday

Jul 18, 2021 · Paresthesia (tingling, numbness) of the extremities (15-38%) Dizziness (11-28%) Dysgeusia (abnormal taste sensation) (6-19%) Insomnia (7-17%) Constipation (6-16%) Dry mouth (5-14%) Headache (5-14%) Nausea (5-13%) Diarrhea (4-11%) Upper respiratory tract infection (4-9%) Aug 3, 2023 · What Is Wegovy? Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e ... It does not making you lose than reaching the idea, it is a compound that can be able to lose weight. It also leads to by increasing their absorption of physical activity and improvement Qsymia Long Term Side EffectsIn clinical studies, phentermine-topiramate reduced body weight by 8.6% to 9.4% more than placebo using a conservative ITT analysis.108. Phentermine-topiramate carries risks of several serious side effects. Notably, topiramate is a recognized teratogen, at least at the higher doses used for the treatment of epilepsy.It is used by certain overweight people, such as those who are obese or have weight -related medical problems. Losing weight and keeping it off can lessen the many health risks that come with ... The Saxenda Savings Card allows you to pay as little as a $25 copay or save up to $200 per Saxenda prescription. The Savings Card program allows for up to 12 benefits annually. There are eligibility requirements, and other restrictions apply. According to GoodRX, out-of-pocket prices range from $1332.59 to $1432.91.Qsymia's results have been clinically tested in two long-term studies with ... QSYMIA CAN CAUSE SERIOUS SIDE EFFECTS, INCLUDING: Birth defects (cleft lip/cleft palate). If you take Qsymia during ...Places you in a long-term behavioral changing plan; The Cons. Serious side-effects; Some people didn’t notice that many benefits; The results they claim are underwhelming; Qsymia Conclusion. Qsymia is an example of a prescription drug for weight loss that might do more harm than good.Nov 2, 2022 · Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use. Feb 1, 2023 · Phentermine is used as part of a short-term plan, along with a low calorie diet, for weight reduction. It is used in obese patients who have not been able to lose weight with diet and exercise alone. Phentermine belongs to the group of medicines known as appetite suppressants. This medicine is available only with your doctor's prescription. Ozempic, a medication used in type 2 diabetes, is currently under review by the FDA to be approved for weight loss in overweight or obese adults. Phentermine may be a more accessible option to help you lose weight, but it should only be used for a few weeks. Both Ozempic and phentermine can help to curb your appetite so that you eat fewer ...The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs—orlistat (Xenical, Alli), phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), liraglutide (Saxenda), and semaglutide (Wegovy)—for long-term use.The SELECT trial is the long-term cardiovascular outcomes trial for Wegovy that aims to assess its effects on heart disease and stroke in patients with overweight and obesity; it is currently ongoing and expected to be completed in September 2023. Anti-obesity medication management: An evolving landscapeJan 16, 2023 · Qsymia is significantly more expensive than phentermine-only pills, costing about $200 per month without insurance. The combined pill has a long list of potential side effects, including severe birth defects if taken while pregnant. This is a newer medication (FDA approval in 2012), so long-term side effects remain relatively unknown. Aug 4, 2022 · Less common. Chest discomfort. decreased urine. dry mouth. fast, irregular, pounding, or racing heartbeat or pulse. loss of appetite. mood changes. muscle pain or cramps. nausea or vomiting. numbness or tingling in the hands, feet, or lips. seizures. Qsymia is prescription-only weight loss medication that contains a combination of phentermine HCl and topiramate extended-release. This drug, which received FDA approval in 2012, helps manage obesity longer-term than phentermine alone, but also carries the risk of additional side effects (1, 2).Phentermine Results after 3 Months. First of all, let us clarify if you take Phentermine HCL without any special diet or exercise plan, it is possible to lose around 8 pounds within the 3 months ...1. Nausea and vomiting. Nausea is the most common semaglutide side effect. Up to 20% of people taking it for Type 2 diabetes reported nausea in clinical trials. Nausea is even more common if you’re taking the higher-dose version for weight loss. Vomiting tends to be less common than nausea.Phentermine is an effective weight loss pill, but due to stimulating effects, it may induce withdrawal symptoms in some people. Withdrawal symptoms occur when the brain is trying to adjust to the new situation. Persons experience symptoms such as fatigue, irritability, bad mood, among others.Oct 14, 2022 · In fact, this sort of weight loss is referred to as yo-yo dieting (yes, even if it comes secondary to the use of prescription medication) and can cause some serious long-term problems. #2. Using Phentermine Daily Can and Dose Cause Metabolic Damage. Perhaps the single biggest reason to avoid using Phentermine is that it can cause something ... Studies show that on average, people taking Topamax lose around 11 lbs. Higher doses and longer duration of use generally result in more weight loss. The most common side effects associated with Topamax for weight loss are abnormal skin sensations (like burning, tingling, numbness), altered sense of taste, and slowed thinking and movements.May 19, 2016 · Long-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances. Oct 26, 2022 · Common Qsymia side effects may include: joint pain, ankle sprain; flu-like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems (insomnia); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, ... However, the EMA has not approved this medication due to its abuse potential, the lack of long-term data on the cardiovascular effects of phentermine, and the cognitive side effects of topiramate—attention, language, and memory impairment . As this drug combination contains phentermine, it is a controlled DEA schedule IV substance.You can do this by taking certain adrenal support supplements, eliminating stressors in your life, eating a healthy diet, taking advantage of low-intensity exercises at night, carbohydrate cycling, and using meditation. Optimizing your adrenal glands for 1-2 months prior to using phentermine may be ideal for many thyroid patients.Jan 6, 2021 · During the last few decades, some anti-obesity drugs were used to treat morbid obesity; however, many of them were removed from the market owing to long-term side effects, particularly cardiovascular issues . Since then, anti-obesity drug development process focusses on both weight loss efficacy and cardiovascular safety. Apr 11, 2017 · Serious side effects vary by drug but can include depression, heart palpitations, fast or irregular heartbeat, increased blood pressure, dizziness, tremors, chest pain, and difficulty breathing ... weight loss. impaired taste (changes in how things taste) trouble with memory. More common side effects in people taking Topamax for epilepsy include: tingling in the legs and arms. loss of ...Feb 14, 2023 · Common side effects of Xenical include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Side effects include: Oily spotting ... Qsymia Dosage and Administration. Take orally once daily in morning. Avoid administration in evening to prevent insomnia ( 2.3 ). Recommended starting dosage is 3.75 mg/23 mg (phentermine mg/topiramate mg) daily for 14 days; then increase to 7.5 mg/46 mg daily ( 2.3 ).Feb 25, 2021 · Ozempic, a medication used in type 2 diabetes, is currently under review by the FDA to be approved for weight loss in overweight or obese adults. Phentermine may be a more accessible option to help you lose weight, but it should only be used for a few weeks. Both Ozempic and phentermine can help to curb your appetite so that you eat fewer ... It is also commonly prescribed to prevent migraines. Mild topiramate side effects include a “pins and needles” feeling, weight loss, and dizziness. Trouble focusing or thinking are also possible, especially when taking higher doses. High body temperature, suicidal thoughts, and eye problems are rare topiramate side effects.The SELECT trial is the long-term cardiovascular outcomes trial for Wegovy that aims to assess its effects on heart disease and stroke in patients with overweight and obesity; it is currently ongoing and expected to be completed in September 2023. Anti-obesity medication management: An evolving landscapeMay 3, 2023 · 1. Nausea and vomiting. Nausea is the most common semaglutide side effect. Up to 20% of people taking it for Type 2 diabetes reported nausea in clinical trials. Nausea is even more common if you’re taking the higher-dose version for weight loss. Vomiting tends to be less common than nausea. Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ... Aug 5, 2020 · As long as you are not taking the medication continuously with no breaks, and will stop the medication eventually, I believe that this is a safe treatment for you. That being said, you mentioned 5 years in the beginning of the question. If you have been taking the medication 3 months on, 1 month off for 5 years, I would consider that long term ... Qsymia may affect how you think and cause confusion, problems with concentration, attention, memory or speech. Tell your healthcare provider if symptoms occur. Slowing of growth. Qsymia may slow the increase in height in children 12 years and older. Increases of acid in bloodstream (metabolic acidosis).This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen. If you are taking any of these drugs: Linezolid or methylene blue. If you are pregnant or may be pregnant. Do not take this drug if you are pregnant. If you are breast-feeding.Feb 28, 2023 · The Saxenda Savings Card allows you to pay as little as a $25 copay or save up to $200 per Saxenda prescription. The Savings Card program allows for up to 12 benefits annually. There are eligibility requirements, and other restrictions apply. According to GoodRX, out-of-pocket prices range from $1332.59 to $1432.91. Phentermine Results after 3 Months. First of all, let us clarify if you take Phentermine HCL without any special diet or exercise plan, it is possible to lose around 8 pounds within the 3 months ...The Bottom Line. Qsymia is a prescription-only weight loss medication that, when used in conjunction with diet and exercise, has a proven track record in overweight and obese individuals. The most common adverse effects are abnormal skin sensations, dizziness, altered taste, insomnia, constipation, and dry mouth, more severe issues can occur.Mar 13, 2023 · weight loss. impaired taste (changes in how things taste) trouble with memory. More common side effects in people taking Topamax for epilepsy include: tingling in the legs and arms. loss of ... Summary. Commonly reported side effects of orlistat include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules.Using nonexposed periods in former users as a comparison achieves partial balance for obesity status. Second, because the signal of potential concern with Qsymia is increased heart rate—an effect that does not persist after the drug is withdrawn—the potential for carryover effects beyond current use was considered remote. Key variablesPhentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use.1. In 2012, a new medication called Qsymia (with both Adipex and Topamax components) became available for weight loss. It was the first FDA approved weight loss drug in its class. The weight loss pill is a combination of 2 existing drugs: phentermine and topiramate. This combination has been shown to be a good tool for weight loss in addition ...Taking this medication late in the day may cause trouble sleeping ( insomnia ). Swallow the capsules whole. Do not crush or chew the capsules. Doing so can release all of the drug at once,...Side Effects of Qsymia. Side effects of Qsymia in patients taking it for up to one year were paraesthesia (tingling or pins-and-needles sensations most often in the hands, feet, or face), dizziness, dysgeusia (distortion of the sense of taste), insomnia, constipation, and dry mouth. This medication can cause a mild (2 bpm) increase in resting ...You can do this by taking certain adrenal support supplements, eliminating stressors in your life, eating a healthy diet, taking advantage of low-intensity exercises at night, carbohydrate cycling, and using meditation. Optimizing your adrenal glands for 1-2 months prior to using phentermine may be ideal for many thyroid patients.Topamax withdrawal can occur when it’s stopped abruptly instead of tapered. The greatest risk is that your seizures worsen. Instead of stopping Topamax at once, your HCP can help you taper your dosage gradually. 7. Gabapentin (Neurontin) Gabapentin (Neurontin) is FDA-approved to treat seizures and nerve pain.trouble sleeping (insomnia) new or worse irritability acting aggressive, being angry, or violent acting on dangerous impulses an extreme increase in activity and talking (mania) other unusual changes in behavior or mood Serious eye problems which include:At 6 months, a year, and 2 years after starting phentermine, weight loss was clinically significantly greater among people who used the medication longer-term (more than a year) or medium-term (more than112 days but less than a year) than in people who used it for only 3 months.Apr 30, 2014 · This review showed that combining low doses of phentermine and topiramate for the treatment of obesity minimized side effects while maintained weight loss efficacy. The side effects were paraesthesia, taste changes and dry mouth. Weight loss induced by the combination was associated with improved BP through one and two years of treatment. Phentermine-Topiramate Capsule, Extended Release Multiphase 24 Hr (Capsule, ER Hr) - Uses, Side Effects, and More Common Brand(S): Qsymia Generic Name(S): phentermine-topiramate 4. Avoid alcohol. Avoid drinking alcohol while taking Qsymia as it can increase your risk of serious side effects, such as central nervous system depression, and an increase in your risk of falls. 5. Don’t skip meals. Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia). 6. Extreme happiness or sadness. Symptoms of dangerously high blood pressure, such as severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, or seizures. These symptoms can indicate a serious phentermine side effect.This review showed that combining low doses of phentermine and topiramate for the treatment of obesity minimized side effects while maintained weight loss efficacy. The side effects were paraesthesia, taste changes and dry mouth. Weight loss induced by the combination was associated with improved BP through one and two years of treatment.In fact, this sort of weight loss is referred to as yo-yo dieting (yes, even if it comes secondary to the use of prescription medication) and can cause some serious long-term problems. #2. Using Phentermine Daily Can and Dose Cause Metabolic Damage. Perhaps the single biggest reason to avoid using Phentermine is that it can cause something ...Objective: The aim of this work was to study weight loss and risk of cardiovascular disease (CVD) or death associated with longer-term phentermine use. Methods: Using electronic health record data, 13,972 adults were identified with a first phentermine fill in 2010 to 2015, creating exposure categories according to a patient's duration of use (referent: ≤ 3 months). 1. Nausea and vomiting. Nausea is the most common semaglutide side effect. Up to 20% of people taking it for Type 2 diabetes reported nausea in clinical trials. Nausea is even more common if you’re taking the higher-dose version for weight loss. Vomiting tends to be less common than nausea.Jan 16, 2023 · Qsymia is significantly more expensive than phentermine-only pills, costing about $200 per month without insurance. The combined pill has a long list of potential side effects, including severe birth defects if taken while pregnant. This is a newer medication (FDA approval in 2012), so long-term side effects remain relatively unknown. Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ...Phentermine is approved for long-term use (>12 weeks) for weight management in combination with topiramate (Qsymia). Phentermine alone continues to be approved for short-term use (e.g., 12 weeks). In reality, phentermine is prescribed off-label to patients for longer than 12 weeks, and a recent study found improved weight loss and no adverse ...Phentermine Results after 3 Months. First of all, let us clarify if you take Phentermine HCL without any special diet or exercise plan, it is possible to lose around 8 pounds within the 3 months ...Phentermine alone is designed for short-term use only, as there are few long-term studies on its safety. One study observed that people experienced no significant side effects when they took ...Qsymia is an appetite suppressant with side effects and it's not clear why it works. It tends to help you feel full. It works for me. But what it helps you do is CICO. For me in particular, it lets me eat one "normal" meal a day and the other meals light. I feel full in the evening so I don't feel hungry.As long as you are not taking the medication continuously with no breaks, and will stop the medication eventually, I believe that this is a safe treatment for you. That being said, you mentioned 5 years in the beginning of the question. If you have been taking the medication 3 months on, 1 month off for 5 years, I would consider that long term ...Phentermine is used as part of a short-term plan, along with a low calorie diet, for weight reduction. It is used in obese patients who have not been able to lose weight with diet and exercise alone. Phentermine belongs to the group of medicines known as appetite suppressants. This medicine is available only with your doctor's prescription.Jun 28, 2023 · Extreme happiness or sadness. Symptoms of dangerously high blood pressure, such as severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, or seizures. These symptoms can indicate a serious phentermine side effect. Common side effects of phentermine and topiramate may include: joint pain, ankle sprain; flu -like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems ( insomnia ); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, thoughts about ...Ozempic, a medication used in type 2 diabetes, is currently under review by the FDA to be approved for weight loss in overweight or obese adults. Phentermine may be a more accessible option to help you lose weight, but it should only be used for a few weeks. Both Ozempic and phentermine can help to curb your appetite so that you eat fewer ...Oct 26, 2022 · Common Qsymia side effects may include: joint pain, ankle sprain; flu-like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems (insomnia); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, ... The Bottom Line. Qsymia is a prescription-only weight loss medication that, when used in conjunction with diet and exercise, has a proven track record in overweight and obese individuals. The most common adverse effects are abnormal skin sensations, dizziness, altered taste, insomnia, constipation, and dry mouth, more severe issues can occur.Phentermine-Topiramate Capsule, Extended Release Multiphase 24 Hr (Capsule, ER Hr) - Uses, Side Effects, and More Common Brand(S): Qsymia Generic Name(S): phentermine-topiramate Side Effects of Qsymia. Side effects of Qsymia in patients taking it for up to one year were paraesthesia (tingling or pins-and-needles sensations most often in the hands, feet, or face), dizziness, dysgeusia (distortion of the sense of taste), insomnia, constipation, and dry mouth. This medication can cause a mild (2 bpm) increase in resting ...COMMON SIDE EFFECTS OF QSYMIA IN CHILDREN 12 YEARS OLD AND OLDER INCLUDE: Depression, dizziness, joint pain, fever, flu, and ankle sprain. POSSIBLE SIDE EFFECTS OF QSYMIA INCLUDE: Mood changes and trouble sleeping. Qsymia may cause depression or mood problems, and trouble sleeping. Tell your healthcare provider if symptoms occur.Oct 27, 2021 · Introduction. The worldwide prevalence of overweight and obesity, defined as having a body mass index (BMI) between 25.0–29.9 kg/m 2 and ≥30.0 kg/m 2, 1 has almost tripled since the 1970s, with nearly 40% of adults being overweight and 13% obese, and these numbers have been steadily increasing. 2 Patients with obesity are at an increased risk of developing comorbidities such as ... The highest dose of Qsymia contains only 15mg of Phentermine, but the average dose of Phentermine (for weight loss when used by itself) is 37.5mg. While it may be nice to have a combination medication, it may actually be better to prescribe both medications individually so you have more control over the dosages of each medication.This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen. If you are taking any of these drugs: Linezolid or methylene blue. If you are pregnant or may be pregnant. Do not take this drug if you are pregnant. If you are breast-feeding.The most common side effects are tingling in the hands and feet, dizziness, change in taste, trouble sleeping, constipation and dry mouth. Qsymia can also increase your resting heart rate, affect ...During the last few decades, some anti-obesity drugs were used to treat morbid obesity; however, many of them were removed from the market owing to long-term side effects, particularly cardiovascular issues . Since then, anti-obesity drug development process focusses on both weight loss efficacy and cardiovascular safety.These are the most common Topamax side effects, according to the manufacturer: Loss of appetite, changes in taste, weight loss, stomach pain, and even anorexia. GI side effects (nausea, diarrhea, indigestion) Tiredness. Paresthesia (tingling or prickling sensations) Speech problems. Cognitive dysfunction (trouble with memory and thinking) Upper ...Feb 14, 2023 · Summary. Commonly reported side effects of orlistat include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules.

Objective: The aim of this work was to study weight loss and risk of cardiovascular disease (CVD) or death associated with longer-term phentermine use. Methods: Using electronic health record data, 13,972 adults were identified with a first phentermine fill in 2010 to 2015, creating exposure categories according to a patient's duration of use (referent: ≤ 3 months).. 314 500 6768

qsymia long term side effects

The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs—orlistat (Xenical, Alli), phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), liraglutide (Saxenda), and semaglutide (Wegovy)—for long-term use. Approved for long-term use? Yes. Qsymia has much lower amounts of phentermine and topiramate than when these drugs are given alone. Side effects: The most common side effects are tingling hands ...This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen. If you are taking any of these drugs: Linezolid or methylene blue. If you are pregnant or may be pregnant. Do not take this drug if you are pregnant. If you are breast-feeding.Oct 26, 2022 · Common Qsymia side effects may include: joint pain, ankle sprain; flu-like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems (insomnia); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, ... Aug 1, 2023 · These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about ... Apr 30, 2014 · This review showed that combining low doses of phentermine and topiramate for the treatment of obesity minimized side effects while maintained weight loss efficacy. The side effects were paraesthesia, taste changes and dry mouth. Weight loss induced by the combination was associated with improved BP through one and two years of treatment. It does not making you lose than reaching the idea, it is a compound that can be able to lose weight. It also leads to by increasing their absorption of physical activity and improvement Qsymia Long Term Side Effects4. Avoid alcohol. Avoid drinking alcohol while taking Qsymia as it can increase your risk of serious side effects, such as central nervous system depression, and an increase in your risk of falls. 5. Don’t skip meals. Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia). 6. From research studies, an outline of the common and rare side effects associated with Qsymia is as follows: Common side effects (reported in more than 1% of patients): Paresthesia (tingling, numbness) of the extremities (15-38%) Dizziness (11-28%) Dysgeusia (abnormal taste sensation) (6-19%) Insomnia (7-17%) Constipation (6-16%)At 6 months, a year, and 2 years after starting phentermine, weight loss was clinically significantly greater among people who used the medication longer-term (more than a year) or medium-term (more than112 days but less than a year) than in people who used it for only 3 months.Taking this medication late in the day may cause trouble sleeping ( insomnia ). Swallow the capsules whole. Do not crush or chew the capsules. Doing so can release all of the drug at once,... At 6 months, a year, and 2 years after starting phentermine, weight loss was clinically significantly greater among people who used the medication longer-term (more than a year) or medium-term (more than112 days but less than a year) than in people who used it for only 3 months..

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